Excessive moisture, dehydration, or frozen/melted agar. Contamination: Any visible growth or excessive bubbles. Purchasing and Access
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However, the decision by CLSI to withdraw the standard reflects a smart consolidation of information. Having separate documents for "Control Materials" (M22) and "Performance Standards" (M100) created a risk of discrepancy between the two. By moving the QC guidelines into M100, CLSI ensures that the acceptable limits for QC strains are updated annually in tandem with the breakpoint changes. clsi m22a3 pdf
There is publicly available. The series appears to have been superseded by the broader CLIA regulatory changes and the introduction of the IQCP framework. The third edition remains the final and most comprehensive version of this standard.
Many hospital networks and academic universities maintain institutional subscriptions to the CLSI eCLIPSE database, granting laboratory staff full digital access to the standard. Excessive moisture, dehydration, or frozen/melted agar
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The 44-page document is structured into 8 main sections, along with several critical tables. Understanding the structure of M22-A3 helps users quickly locate the specific information they need. Having separate documents for "Control Materials" (M22) and
File and maintain the manufacturer’s QC certificates for all exempt media.
M22-A3 emphasizes that no system is 100% accurate for all NFB species.